Veterinary Archives, Vol. 91 No. 5, 2021.
Case report
https://doi.org/10.24099/vet.arhiv.0893
Combination of photodynamic therapy and phototherapy for the treatment of cutaneous open wounds in dogs - case reports
Alexandre B. A. Sampaio
; Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Botucatu, SP, Brazil
Sheila C. Rahal
orcid.org/0000-0002-9211-4093
; Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Botucatu, SP, Brazil
Marina P. Branco
; Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Botucatu, SP, Brazil
Rebeca B. Abibe
; Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Botucatu, SP, Brazil
Henrique O. Dorth
; Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Botucatu, SP, Brazil
Jeniffer G. F. Coris
; Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Botucatu, SP, Brazil
Luciana Almeida-Lopes
; Research and Education Center for Photo Therapy in Health Sciences - NUPEN , São Carlos, SP, Brazil
Abstract
The evolution of cutaneous open wounds was evaluated in five client-owned dogs treated with photodynamic therapy (PDT), mediated by methylene blue and phototherapy with light-emitting diodes (LED) as the light source. On the first day of treatment, the wound was irrigated with sterile 0.9% sodium chloride solution, the surface was dried, and 3% solution of hydrogen peroxide soaked for 1 minute. The hydrogen peroxide was mechanically removed and, immediately after, 0.01% methylene blue was used in the wound for five minutes, after which a cluster of red LEDs (650 - 670 nm wavelength, 350 mW power, and irradiance of 200 mW/cm2) was used. Subsequently, single phototherapy sessions, every 48 hours or more, were applied until wound healing. In general, 24J was used for PDT and 12J for phototherapy. In all cases, the cutaneous open wounds treated with PDT associated with phototherapy healed without complications, and it may be considered as a treatment option, especially for extensive lesions.
Keywords
healing; photodynamic therapy; light-emitting diode; wound
Hrčak ID:
271614
URI
Publication date:
12.12.2021.
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