Original scientific paper

https://doi.org/10.24099/vet.arhiv.1087

Changes in the lipid profile of neutered cats’ blood in cases of obesity and diabetes

Inna V. Chala orcid.org/0000-0001-9073-2851 ; Department of Parasitology, Veterinary-Sanitary Expertise and Zoohygiene, Faculty of Veterinary Medicine, Polissia National University, Ukraine
Diana V. Feshchenk orcid.org/0000-0002-4811-2488 ; Department of Parasitology, Veterinary-Sanitary Expertise and Zoohygiene, Faculty of Veterinary Medicine, Polissia National University, Ukraine
Oksana A. Dubova orcid.org/0000-0002-8303-573X ; Department of Parasitology, Veterinary-Sanitary Expertise and Zoohygiene, Faculty of Veterinary Medicine, Polissia National University, Ukraine
Tetiana I. Bakhur orcid.org/0000-0001-8271-8267 ; Department of Parasitology and Pharmacology, Faculty of Veterinary Medicine, Bila Tserkva National Agrarian University, Bila Tserkva, Ukraine
Oksana A. Zghozinska orcid.org/0000-0003-4622-6307 ; Department of Parasitology, Veterinary-Sanitary Expertise and Zoohygiene, Faculty of Veterinary Medicine, Polissia National University, Ukraine
Vasyl S. Rusak ; Department of internal animal diseases and physiology, Faculty of Veterinary Medicine, Polissia National University, Zhytomyr, Ukraine

Abstract

The aim of the present study was to examine the lipid profile, lipid fractions and the lipid peroxidation state in the blood of neutered cats with obesity and diabetes. Three groups of neutered cats (males and females) were formed for the study. We compared cats with obesity (7-9 points on a 9-point BCS scale), with obesity complicated by diabetes, and clinically healthy animals with normal body condition scores (4-5 BCS points). Lipidogram parameters, fractions of high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL), chylomicrons (CM), lipid peroxidation products (POL) - lipid hydroperoxides (GPL) and malondialdehyde (MDA) were analysed. In obese cats, a decrease in HDL and phospholipids was observed, and an increase in LDL, VLDL, CM, triglycerides, and cholesterol. No significant differences in lipid and lipoprotein metabolism between neutered females and males were found. A tendency towards increasing concentrations of lipoproteins, triglycerides and cholesterol in males, as well as an increase in phospholipids in females was found. In cats with obesity and associated diabetes, the ratio of phospholipids: cholesterol was less than one, while in healthy cats - more than one. Obesity and diabetes initiate POL and increased concentrations of GPL and MDA, which were the highest in the blood of females with associated pathology.

Keywords

cat; obesity; triglycerides; cholesterol; phospholipids; lipid hydroperoxides

Hrčak ID:

271890

URI

https://hrcak.srce.hr/271890

Publication date:

27.1.2022.

Article data in other languages: croatian

Visits: 1.426 *