Original scientific paper
Risk Factor Analysis and Diagnoses of Coronary Heart Disease in Patients with Hypercholesterolemia from Croatian Zagorje County
Ksenija Pešek
Damir Buković
Tomislav Pešek
Slavko Orešković
Darko Milinović
Marko Rukavina
Mato Pavić
Marija Zlojtro
Abstract
Our aim is to determine if there exists a difference in risk factors and diagnosis between patients being treated on internal
medicine ward for coronary heart disease who have higher levels of cholesterol in their blood and other patients,
without proved higher levels of cholesterol, hospitalized for coronary heart disease. We followed patients hospitalized in
General Hospital Zabok for coronary heart disease for the period between 2004–2006y. On admission patients were diagnosed
with coronary heart disease based on laboratory markers specific for the disease (CK, troponin, LDH,CRP), ECG
and history taking. We analyzed two groups of patients for diagnosis and risk factors on discharge from the hospital: one
group with proven hypercholesterolemia, the other with coronary heart disease without hypercholesterolemia. For the duration
of the study there were no significant alternations concerning risk factors for coronary heart disease, and hypertension
was the most prevalent of these factors in both groups. Values of HDL, as an indirect indicator of coronary heart
disease, were lower in both groups for the duration of the study. In group of patients with hypercholesterolemia myocardial
infarction with a ST segment elevation, as a discharge diagnosis, was a more prevalent complication of the disease,
while for the group of patients without hypercholesterolemia stable angina pectoris was more prevalent and this is explained
as atheroma plaque stabilization when there are normal values of blood cholesterol.
Keywords
hypercholesterolemia; prevalence of risk factors; cardiovascular disease; coronary heart disease
Hrčak ID:
27223
URI
Publication date:
7.7.2008.
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