Conference paper

EATING DISORDERS AND PSYCHOFARMACHOLOGY: RETHINK THE TREATMENT OF EATING DISORDERS

Leonardo Mendolicchio ; IRCCS Istituto Auxologico, U.O. Eating Disorder "San Giuseppe", Verbania, Italy; Food For Mind Innovetion Hub - Outpatient center of eating disorder, Milano, Italy
Emanuela Apicella ; IRCCS Istituto Auxologico, U.O. Eating Disorder "San Giuseppe", Verbania, Italy; Food For Mind Innovetion Hub - Outpatient center of eating disorder, Milano, Italy
Enrica Ventura ; IRCCS Istituto Auxologico, U.O. Eating Disorder "San Giuseppe", Verbania, Italy

Abstract

The pharmacological approach to eating disorders (ED) is effective in a few conditions, and to date, no treatment has shown
certain efficacy in treating patients with this disorder. Furthermore, attempts to regulate hunger and satiety through modulation
pharmacological effects of neurotransmitters and neuropeptides have shown only short-term benefit. However, in light of the serious
impact of DCA on patients and the scarcity of non-pharmacological therapeutic approaches, research in this area should not be
abandoned, also because new generation "molecules" become increasingly available.
Many studies looked at efficacy of antipsychotics, Tryciclics, SSRI, mood stabilizers in the treatment of ED. Gabaergic circuit,
the opioid one are extremely involved in the neurohormonal mechanisms of regulation of dietary behaviors and that molecules that
influence these circuits could be used in the pharmacological treatment of ED as already happens in the case of Naltrexone,
gabapentine or gabaergic drugs.

Keywords

anorexia nervosa; bulimia nervosa; eating disorders; opioid system; gabaergic system

Hrčak ID:

274028

URI

https://hrcak.srce.hr/274028

Publication date:

16.9.2021.

Visits: 659 *