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Acta Dermatovenerologica Croatica, Vol. 29 No. 1, 2021.

Original scientific paper

Analysis of Coexistence of Oral and Cutaneous Lesions in 253 Patients with Lichen Planus – Single-center Retrospective Analysis

Vladimíra Radochová orcid id orcid.org/0000-0002-0212-4328 ; Department of Dentistry, Charles University, Faculty of Medicine and University H Hradec Králové, Hradec Králové, Czech Republic
Radovan Slezák ; Department of Dentistry, Charles University, Faculty of Medicine and University H Hradec Králové, Hradec Králové, Czech Republic
Romana Koberová Ivančaková ; Department of Dentistry, Charles University, Faculty of Medicine and University H Hradec Králové, Hradec Králové, Czech Republic

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Abstract

Lichen planus (LP) is a chronic inflammatory disorder that especially
affects the skin, mucous membranes, or both. The aim of the study
was to determine the clinical characteristics of patients with LP in the oral
cavity and concomitant cutaneous lesions and compare their outcomes with
those without cutaneous lesions. 253 records of patients with confirmed diagnosis
of oral lichen planus (OLP) were retrospectively analyzed. The following
clinical data were obtained from the medical charts: sex, age, clinical
presentations of OLP, distributions of the lesions, presence of symptoms, extra
oral manifestations of lichen planus, presence of systemic diseases, and
treatment provided. The group of patients with cutaneous manifestations
was compared for possible clinical differences to those without. Cutaneous
lesions were present in 18.2% (46/253) of patients. Significantly more
patients with cutaneous lesions had other extra oral manifestations (26.1%
versus 1.0%, P<0.00001). Lips were significantly more affected in patients
with cutaneous presentation (41.3% versus 16.9%, P=0.00006). Ulcerative
OLP was more frequent in patients with cutaneous lesions (23.9% versus
10.6%, P=0.0266). Patients with cutaneous manifestations needed significantly
more systemic treatment with systemic steroids (10.9% versus 3.4%,
P=0.0466). Patients with cutaneous lesions were more symptomatic and
tended to require more treatment than patients with OLP who only had oral
involvement

Keywords

oral lichen planus, clinical features, extra-oral manifestation

Hrčak ID:

274437

URI

https://hrcak.srce.hr/274437

Publication date:

17.3.2021.

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