Original scientific paper

https://doi.org/10.20471/acc.2021.60.04.11

Effect of Dipping Pattern of Gestational Hypertension on Maternal Symptoms and Physical Findings, Birth Weight and Preterm Delivery

Đorđe Ilić ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Department of Obstetrics and Gynecology, Clinical Center of Vojvodina, Novi Sad, Serbia
Aleksandra Ilić ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia
Snežana Stojšić ; Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia
Anastazija Stojšić-Milosavljević ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia
Jelena Papović ; Institute of Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia
Dragana Grković ; Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia
Olivera Rankov ; Department of Obstetrics and Gynecology, Clinical Center of Vojvodina, Novi Sad, Serbia
Aleksandra Milovančev ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia
Lazar Velicki ; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia; Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia

Abstract

The study aimed to determine if the non-dipping pattern of blood pressure (BP)
influences preterm delivery in gestational hypertension (GH), but also maternal clinical findings and
birth weight. Sixty women with GH, i.e. 30 women with a dipping BP profile (control group) and 30
non-dippers (study group), were included in the study. Echocardiography was performed in all subjects,
as well as ambulatory blood pressure monitoring (ABPM) during third trimester. ABPM was
repeated 6-8 weeks after delivery. Thirteen women with preterm delivery were classified as non-dippers
and only four as dippers (p=0.01). The average and peak systolic and diastolic night-time BP had
negative linear correlation with birth weight (p<0.0005). Total vascular resistance (p<0.0005) and
mass index (p=0.014) were significantly higher as compared with women with term delivery, while
ejection fraction (EF) (p=0.007) and circumferential systolic velocity (p=0.042) were significantly reduced
in the preterm delivery group. Multivariate binary logistic regression identified the average
night-time systolic BP, left ventricular mass index and EF as independent predictors of preterm delivery.
Study results suggested a relationship of the non-dipping BP pattern in GH with preterm delivery,
birth weight, and maternal clinical findings.

Keywords

Pregnant women; Echocardiography; Hemodynamics; Blood pressure; Prenatal care

Hrčak ID:

275499

URI

https://hrcak.srce.hr/275499

Publication date:

1.12.2021.

Article data in other languages: croatian

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