Acta clinica Croatica, Vol. 60. No. 4., 2021.
Original scientific paper
https://doi.org/10.20471/acc.2021.60.04.12
Higher Frequency of Germinal Matrix-Intraventricular Hemorrhage in Moderate and Late Preterm and Early Term Neonates with Intrauterine Growth Restriction Compared to Healthy Ones
Radmila Mileusnić-Milenović
; Institute of Neonatology, Belgrade, Serbia
Abstract
Germinal matrix-intraventricular brain hemorrhage is mostly found in preterm
neonates, but may also occur in term neonates. The aim of this study was to analyze the prevalence and
severity of this type of hemorrhage in moderate and late preterm and early term neonates with intrauterine
growth restriction. In the prospective analysis, 100 newborns were examined, i.e. 70 with intrauterine
growth restriction and 30 as a control group. Study subjects were neonates from 32 0/7 to
38 6/7 gestational weeks. Body weight, body length, head circumference and ponderal index at birth
were analyzed. Hemorrhage was assessed by cranial ultrasound using Papile classification. Out of 70
neonates with intrauterine growth restriction, germinal matrix-intraventricular hemorrhage was not
found in 36 (51.43%) neonates, 31 (44.29%) had hemorrhage grade 1, and three (4.29%) had hemorrhage
grade 2, which was statistically significant (p<0.001) in relation to the control group. There were
no neonates with hemorrhage grade 3 or 4. The predominant type of germinal matrix-intraventricular
hemorrhage in the intrauterine growth restriction group was hemorrhage grade 1. Germinal matrixintraventricular
hemorrhage was more often present in the intrauterine growth restricted neonates
than in the control group.
Keywords
Neonates; Growth restriction; Germinal matrix-intraventricular hemorrhage; Cranial ultrasound
Hrčak ID:
275500
URI
Publication date:
1.12.2021.
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