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Recurrent deep venous thrombosis in a cancer patient during coumarin therapy – a case report

Irena Mihić-Lasan ; Department for Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Marija Skoko ; Department for Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Jelena Culej ; Department for Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Tiha Vučemilo ; Department for Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Gorana Krajačić-Karas ; Department for Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Deana Šturm ; Department for Transfusion Medicine, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Abstract

Cancer patients have a four-fold increased risk of developing venous thromboembolism (VTE), relative to the general population. Affecting about 15 % of patients with cancer, it is presenting a great challenge for prophylaxis and treatment. The standard treatment for acute venous thromboembolism consists of initial therapy with low-molecular-weight-heparin (LMWH) followed by long-term therapy with an oral anticoagulant. Despite the use of standard anticoagulant therapy, there is also a three-fold risk of recurrent venous thromboembolism for cancer patients.
In this case report the authors report a case of a 60 year old patient with carcinoma of unknown primary site, who despite standard anticoagulant therapy developed recurrent deep vein thrombosis.

Keywords

cancer; recurrent venous thromboembolism; anticoagulant therapy; LMWH

Hrčak ID:

275971

URI

https://hrcak.srce.hr/275971

Publication date:

25.11.2012.

Article data in other languages: croatian

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