Veterinary Archives, Vol. 92 No. 2, 2022.
Case report, case study
https://doi.org/10.24099/vet.arhiv.1406
A subvulvar leiomyosarcoma in a Simmental cow - a case report
Ahmet Uyar
; Department of Pathology, Faculty of Veterinary Medicine, Mustafa Kemal University, Hatay, Turkey
Erkan Duz
; Gevas Vocational School of Higher Education, Van Yuzuncu Yil University, Van, Turkey
Omer F. Keles
; Department of Pathology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van, Turkey
Turan Yaman
; Department of Pathology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van, Turkey
Zabit Yener
; Department of Pathology, Faculty of Veterinary Medicine, Van Yuzuncu Yil University, Van, Turkey
Abstract
In this case, a mass located subcutaneously in the perineal subvulvar region of a six-year-old Simmental cow was examined clinically, pathomorphologically and immunohistochemically. Macroscopically, the solitary, hitishyellow- tumor mass was 19x15x6 cm in size, weighed 1610 grams, and had a lobular structure with a few small cystic formations in the section. Histopathological examination revealed that the tumor parenchyma had smooth muscle-like cells with abundant cytoplasm, pleomorphic cells with blunt-ended or cigar-shaped nuclei, anisocytosis, anisokaryosis and karyomegaly. Immunohistochemically, strong positive expression for α-SMA, vimentin, Ki67 and slight positive for desmin were found, while immulolabeling for pancytokeratin (AE1/AE3), S-100, CD31 and CD34 were negative. In conclusion, on the basis of these findings, the tumor was diagnosed as leiomyosarcoma.
Keywords
surgery; histopathology; α-SMA; vimentin; desmin; Ki67; perineal subvulvar leiomyosarcoma; Simmental cow
Hrčak ID:
278040
URI
Publication date:
19.5.2022.
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