Original scientific paper
https://doi.org/10.3325/cmj.2021.62.318
Clinical application of the RONNA G4 system – preliminary validation of 23 robotic frameless brain biopsies
Domagoj Dlaka
; Department of Neurosurgery, Dubrava University Hospital, Zagreb, Croatia
Marko Švaco
; Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia
Darko Chudy
; Department of Neurosurgery, Dubrava University Hospital, Zagreb, Croatia
Bojan Jerbić
; Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia
Bojan Šekoranja
; Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia
Filip Šuligoj
; Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia
Josip Vidaković
; Faculty of Mechanical Engineering and Naval Architecture, University of Zagreb, Zagreb, Croatia
Fadi Almahariq
; Department of Neurosurgery, Dubrava University Hospital, Zagreb, Croatia
Dominik Romić
; Department of Neurosurgery, Dubrava University Hospital, Zagreb, Croatia
Marina Raguž
orcid.org/0000-0001-9203-7254
; Department of Neurosurgery, Dubrava University Hospital, Zagreb, Croatia
Abstract
Aims To report the outcomes of robot-assisted brain biopsies performed using a novel RONNA G4 system. The system was developed by a research group from the Faculty
of Mechanical Engineering and Naval Architecture and a
team of neurosurgeons from Dubrava University Hospital,
University of Zagreb School of Medicine.
Methods This prospective study included 49 biopsies
analyzed during one year: 23 robotic frameless and 26
frame-based Leksell stereotactic biopsies. We analyzed the
presenting symptoms, tumor range and location, postoperative complications, pathohistological diagnosis, diagnostic yield, as well as operation and hospitalization duration. The target point error was calculated to assess the
accuracy of the RONNA system.
Results No postoperative mortality, morbidity, or infections were observed. In the frameless robotic biopsy
group, only one pathohistological diagnosis was inconclusive. Therefore, the diagnostic yield was 95.6% (22/23),
similar to that of the framebased Leksell stereotactic biopsy group (95.1% or 25/26). The average target point error
in the frameless robotic biopsy group was 2.15±1.22 mm
(range 0.39-5.85).
Conclusion The RONNA G4 robotic system is a safe and
accurate tool for brain biopsy, although further research
warrants a larger patient sample, comparison with other
robotic systems, and a systematic analysis of the entry and
target point errors
Keywords
Hrčak ID:
278145
URI
Publication date:
26.8.2021.
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