Original scientific paper

https://doi.org/10.20471/acc.2022.61.01.04

Long-Term Survival Effects of Preoperative Breast MRI in Patients with Breast-Conserving Surgery

Ahmet Serkan Ilgun orcid.org/0000-0002-4862-2891 ; Department of Surgery, Demiroglu Bilim University, Istanbul, Turkey
Dauren Sarsenov ; Department of Surgery, Mater Dei Hospital, Msida, Malta
Gul Alco ; Department of Radiation Oncology, Gayrettepe Florence Nightingale Hospital, Istanbul, Turkey
Alper Ozturk ; Department of Surgery, Biruni University Medical School, Istanbul, Turkey
Filiz Agacayak ; Department of Radiology, Istanbul Florence Nightingale Hospital, Istanbul, Turkey
Filiz Elbuken ; Department of Radiology, Yeditepe University Medical School, Istanbul, Turkey
Zeynep Erdogan ; Physical Therapy and Rehabilitation Center, Biruni University Medical School, Istanbul, Turkey
Kezban Nur Pilanci ; Department of Medical Oncology, Memorial Bahcelievler Hospital, Istanbul, Turkey
Cetin Ordu ; Department of Medical Oncology, Gayrettepe Florence Nightingale Hospital, Istanbul, Turkey
Fatma Aktepe ; Department of Pathology, Sisli Memorial Hospital, Istanbul, Turkey
Gursel Soybir orcid.org/0000-0003-0626-0105 ; Department of Surgery, Sisli Memorial Hospital, Istanbul, Turkey
Vahit Ozmen ; Department of Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

Abstract

The benefit of breast magnetic resonance imaging (MRI) in breast-conserving
surgery (BCS) is unclear. Our study compared breast cancer patients with and without preoperative
breast MRI and their long-term oncologic outcomes are reported. A total of 1378 BCS cases with early
breast cancer between 1996 and 2017 were reviewed. Patients with carcinoma in situ or neoadjuvant
treatment or having breast MRI after tumor excision were excluded. Of 1378 patients, 270 (19.5%)
had preoperative MRI. There were no significant differences regarding T and N stage and molecular
subtypes between the groups. Surgical margins were significantly wider in the breast MRI group.
Five-year overall survival (OS) was 96.9% in the MRI group and 94.3% in the control group, and
this difference was not significant (p=0.11). Five-year local-regional recurrence-free survival (LRFS)
was not significantly different either (98.8% and 96.5%, respectively, p=0.41). When analyses were
repeated only for patients with hormone receptor-negative or triple-negative breast cancer, there was
still no significant difference in OS, LRFS, or disease-free survival. In conclusion, MRI does not seem
necessary in all patients undergoing BCS. New prospective randomized controlled trials are needed to
determine appropriate use of preoperative MRI and its effects on oncologic outcomes in early breast
cancer patients.

Keywords

Breast cancer; Breast MRI; Breast-conserving surgery; Overall survival; Local failure; Oncologic outcome

Hrčak ID:

280104

URI

https://hrcak.srce.hr/280104

Publication date:

1.3.2022.

Article data in other languages: croatian

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