Original scientific paper

https://doi.org/10.20471/acc.2022.61.01.09

Mineral Bone Density and Vitamin D Levels in Patients with Psoriatic Arthritis

Marina Vekić Mužević ; Department of Dermatology and Venereology, Osijek University Hospital Center, Osijek, Croatia; Department of Infectious Diseases and Dermatology and Venereology, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia
Darko Biljan ; Department of Dermatology and Venereology, Osijek University Hospital Center, Osijek, Croatia; Department of Infectious Diseases and Dermatology and Venereology, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia
Marija Šola ; Department of Dermatology and Venereology, Osijek University Hospital Center, Osijek, Croatia; Department of Infectious Diseases and Dermatology and Venereology, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia
Igor Kuric ; Department of Dermatology and Venereology, Osijek University Hospital Center, Osijek, Croatia;
Dario Mužević ; Department of Neurology and Neurosurgery, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine, Osijek, Croatia
Elvira Lazić Mosler ; Catholic University of Croatia, Zagreb, Croatia; Dr. Ivo Pedišić General Hospital, Sisak, Croatia

Abstract

The objective of this study was to explore the possible differences in bone mass
density (BMD) and markers of bone metabolism between patients with psoriasis with concomitant
psoriatic arthritis (PsA) and patients with psoriasis only (PV). A comparable sample of both types of
patients were included in analysis. In all patients, vitamin D serum levels along with inflammatory
markers and parathyroid hormone (PTH) were measured. BMD was assessed with dual-energy x-ray
absorptiometry scan in axial and appendicular skeleton. Patients with PsA tended to have decreased
BMD in axial skeleton, while BMD in appendicular skeleton was comparable between the groups.
No statistically significant correlation was found of inflammatory markers, vitamin D and PTH levels
with BMD in either patient group. A negative correlation was recorded between vitamin D serum
concentration and PTH levels.

Keywords

Psoriasis; Arthritis, psoriatic; Bone mass density; Vitamin D

Hrčak ID:

280119

URI

https://hrcak.srce.hr/280119

Publication date:

1.3.2022.

Article data in other languages: croatian

Visits: 1.379 *