Original scientific paper

Ultrasound-guided percutaneous fine-needle biopsy of the mediastinum

Igor Puljić ; University Department of Thoracic Radiology, Clinic for Pulmonary Diseases «Jordanovac», Zagreb, Croatia
Zlata Ivanovi-Herceg ; University Department of Thoracic Radiology, Clinic for Pulmonary Diseases «Jordanovac», Zagreb, Croatia
Marijan Gorečan ; University Department of Thoracic Radiology, Clinic for Pulmonary Diseases «Jordanovac», Zagreb, Croatia
Inja Neralić-Meniga ; University Department of Thoracic Radiology, Clinic for Pulmonary Diseases «Jordanovac», Zagreb, Croatia
Jelena Popić ; University Department of Thoracic Radiology, Clinic for Pulmonary Diseases «Jordanovac», Zagreb, Croatia

Abstract

The clinicoradiological diagnostic possibilities in mediastinal processes have improved with the introduction of percutaneous and endoscopic biopsies. The aim of this paper is to evaluate the diagnostic reliability of percutaenous mediastinal biopsies (PMB) with a fine needle under ultrasound guidance in patients with a mediastinal mass.
73 PMB with ultrasound guidance have been performed in 66 patients. In this investigation, only patients with primary or secondary solid or cystic formations of the anterior and posterior mediastinum have been included. Patients with achalasia of the oesophagus, diverticles, herniation, mediastinitis and vascular changes have been excluded by conventional radiologic means (summary chest radiographs in two projections), and when required by additional methods (tomography, ultrasound, CT, angiography). The material obtained was examined cytologically. The cytologic results of fine-needle PMB were verified histologically after surgery, surgical biopsies, cytochemical and microbiologic examinations in addition to clinical and radiologic follow-up. The specificity, sensitivity and accuracy of radiological and PMB results was calculated.
A microscopic diagnosis was established in all examined cases: primary malignant processes 31 (46.97%), metastases 14 (21.21%), benign tumors 6 (9.09%), inflammation 9 (13.64%), thyroid goiter and sarcoidosis 6 (9.09%). A high degree of accuracy (90%), specificity (100%) and sensitivity (100%) was obtained. There were no complications.
The diagnostic safety of a technically simple, rapid and low cost method has been established, as a frequent alternative to open surgical biopsy and other biopsies under ionizing radiation devices.

Keywords

ultrasound; mediastinum; biopsy; fine-needle; mediastinal neoplasms; ultrasonography; interventional

Hrčak ID:

281539

URI

https://hrcak.srce.hr/281539

Publication date:

30.11.2005.

Article data in other languages: croatian

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