Original scientific paper

https://doi.org/10.20471/acc.2022.61.03.11

Relationship between Body Mass Index and Patohistological Features of Thyroid Cancer

Željko Zubčić ; Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty Osijek, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital Centre Osijek, Osijek, Croatia
Hrvoje Mihalj ; Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty Osijek, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital Centre Osijek, Osijek, Croatia
Anamarija Šestak ; Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty Osijek, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital Centre Osijek, Osijek, Croatia
Andrijana Včeva ; Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty Osijek, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital Centre Osijek, Osijek, Croatia
Ivan Abičić ; Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty Osijek, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital Centre Osijek, Osijek, Croatia
Tihana Mendeš ; Department of Otorhinolaryngology and Maxillofacial Surgery, Medical Faculty Osijek, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Clinical Hospital Centre Osijek, Osijek, Croatia

Abstract

Available studies report conflicting results on the association of body mass index
(BMI) and pathohistological features of thyroid cancer. This study aimed to investigate the relationship
between BMI and the pathohistological features of different thyroid cancer types. We analyzed
the following data from 95 patients with thyroid cancer: age, gender, BMI, pathohistological characteristics
of cancer (tumor size, multifocality, lymphovascular invasion, extrathyroidal invasion) and the
presence of regional metastases. The BMI of all patients with thyroid cancer was 27.1 ± 4.2. Significantly
more patients with obesity class I had cancer size less than 2 cm (p = 0.02). There is a significant
association between BMI and extrathyroid invasion (p = 0.03; OR, 1.18), but not with lymphovascular
invasion, tumor size, and multifocality. We can conclude that although obesity is a risk factor for the
development of thyroid cancer, higher BMI is only partially associated with more aggressive pathohistological
features of thyroid cancer.

Keywords

Thyroid Cancer; Body Mass Index; Lymphovascular Invasion; Multifocality; Extrathyroidal Invasion

Hrčak ID:

296131

URI

https://hrcak.srce.hr/296131

Publication date:

1.11.2022.

Article data in other languages: croatian

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