Original scientific paper
https://doi.org/10.20471/acc.2023.62.s2.11
Kidney Cancer in Croatia – Trends in Incidence and Mortality in the 21st Century
Mario Šekerija
orcid.org/0000-0001-7508-1501
; Division for Epidemiology and Prevention of Non-communicable Chronic Diseases, Croatian Institute of Public Health, Zagreb, Croatia; University of Zagreb, School of Medicine, Zagreb, Croatia
*
Maša Alfirević
orcid.org/0000-0003-1800-3544
; Department of Urology, Sveti Duh University Hospital, Zagreb, Croatia
Petra Čukelj
; Division for Epidemiology and Prevention of Non-communicable Chronic Diseases, Croatian Institute of Public Health, Zagreb, Croatia
Ivana Brkić Biloš
; Division for Epidemiology and Prevention of Non-communicable Chronic Diseases, Croatian Institute of Public Health, Zagreb, Croatia
Tomislav Kuliš
orcid.org/0000-0002-0895-5691
; University of Zagreb, School of Medicine, Zagreb, Croatia; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia
* Corresponding author.
Abstract
Kidney cancer is estimated to be responsible for more than 400 000 new cancer cases
and 180 000 cancer deaths a year. Its incidence is increasing in the majority of developed countries, due
to an increased prevalence of recognized risk factors such as smoking, alcohol use and obesity, as well as
incidental findings on unrelated diagnostic imaging procedures. Mortality is decreasing in the majority
of European countries, due to improvements in treatment and stage at diagnosis shift with more tumors
being diagnosed at an early stage. In this paper, we present kidney cancer incidence and mortality trends
in Croatia using joinpoint regression analysis. The incidence was rising throughout the 2001-2019 period,
with an annual percent change (APC) of 2.5%; more so in men (APC of 2.5%) than in women
(APC of 2.2%). Mortality increased during the 2001-2014 period (APC of 2.4%), but started to decrease
in recent years (APC -2.7%, 2014-2020). Unlike sex differences observed in other European countries,
with more favorable mortality trends found in women, our study showed a constant increase in mortality
in women (APC of 1.2%) and a recent decrease in mortality in men, starting in 2013 (APC of -2.8%),
after a period of increase from 2001 (APC of 3.3%).
Keywords
Kidney cancer; Incidence; Mortality; Joinpoint regression; Croatia
Hrčak ID:
309988
URI
Publication date:
31.7.2023.
Visits: 910 *