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Acta clinica Croatica, Vol. 62. No. Supplement 2, 2023.

Professional paper

https://doi.org/10.20471/acc.2023.62.s2.21

Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia

Mirko Bakula orcid id orcid.org/0000-0003-4612-3578 ; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia *
Dinko Hauptman ; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia
Tvrtko Hudolin ; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia
Sandra Nađ Škegro ; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia
Katarina Ivana Tudor ; Department of Neurology, Zagreb University Hospital Center, Zagreb, Croatia
Branko Bakula ; Department of Surgery, Sveti Duh University Hospital, Zagreb, Croatia
Željko Kaštelan ; Department of Urology, Zagreb University Hospital Center, Zagreb, Croatia

* Corresponding author.

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Abstract

Sacral neuromodulation (SNM) is a safe, efficacious, and minimally invasive advanced
therapy that involves electrical stimulation to sacral nerve root to modulate neural pathway.
Indications for SNM include symptoms of overactive bladder (OAB), urinary incontinence, urinary
retention, urgency and frequency and, regarding bowel dysfunction, fecal incontinence . In Europe and
Canada, indication is also established for chronic constipation. The mechanism of action is still not fully
elucidated and complete understanding is yet to be determined. It is proposed that SNM modulates
neural circuits in both central and peripheral pathways, thus having an impact on the brain, as well as on
the bladder-targeting neuronal activity. Another possible significant effect on irregular bladder activity
is through inhibition of the bladder afferent pathways by stimulation of the pudendal nerve. Over the
past two decades, with more than 300 000 treated patients, SNM has confirmed its efficacy to relieve
refractory OAB symptoms, as well as urinary retention or fecal incontinence. First SNM applications in
Croatia were uneventful and we are glad to offer our patients this novel therapy in the future.

Keywords

Sacral neuromodulation; Overactive bladder; Croatia

Hrčak ID:

310130

URI

https://hrcak.srce.hr/310130

Publication date:

31.7.2023.

Article data in other languages: croatian

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