Conference paper
Exercise and Allergic Diseases
Tajana Klepac Pulanić
Jelana Macan
Davor Plavec
Božica Kanceljak Macan
Abstract
The aim of this study was to compare exercise-induced bronchial reaction between healthy control subjects and subjects with allergic rhinitis (AR) and allergic asthma (AA). It included 16 controls, 16 subjects with AR and 19 subjects with AA. A skin prick test, pulmonary function test, histamine challenge test and exercise challenge test (ECT) were performed in all subjects. Bronchial reaction to exercise was expressed as the fall index FEV1 (%), AUC0-30 (min x %), and fall index FEF25-75 (%). After ECT, subjects with AA had a significantly greater bronchial reaction to exercise than subjects with AR and controls (respective fall index FEV1 8.4, 2.9, and 2.4 %, P=0.0083; AUC0-30 127.7, 29.6, and 33.1 min x %, P=0.025; and fall index FEF25-75 14.6, 0.06, and 1.9 %, P<0.001). No difference was found between subjects with AR and controls. In conclusion, ECT induced a significantly greater bronchial reaction in patients with AA and bronchial hyperreactivity to histamine than in patients with AR and bronchial normoreactivity to histamine and controls. This difference was not found between subjects with AR and controls.
Keywords
allergic asthma; allergic rhinitis; bronchial reactivity; exercise-induced asthma; exercise test; respiratory function test
Hrčak ID:
311
URI
Publication date:
14.6.2004.
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