Professional paper
https://doi.org/10.20471/LO.2023.51.02-03.15
Advancements in rectal cancer treatment: the role of short-course radiotherapy-comprehensive overview
Ema Muše
; Division of Oncology and Radiotherapy, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ira Renko
orcid.org/0009-0007-0368-6502
; University of Zagreb, Faculty of Food Technology and Biotechnology, Zagreb, Croatia
*
Ines Trkulja
; Institute of Emergency Medicine Sisak-Moslavina Country, Sisak, Croatia
Martina Mikulandra
; Division of Oncology and Radiotherapy, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Andrej Vrdoljak
; University of Zagreb, School of Medicine, Zagreb, Croatia
Meliha Solak
; 1 Division of Oncology and Radiotherapy, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
* Corresponding author.
Abstract
Rectal cancer is a disease in which malignant cells form in the epithelium of the rectum. Symptoms of rectal cancer are changes in bowel habits or blood in stool. It is curable, especially if detected early. Patients undergo treatment that includes surgery, chemotherapy, and radiotherapy. Radiotherapy uses energy sources to eliminate cancer cells. Short-course radiotherapy (SCRT) is a neoadjuvant form of treatment for resectable cancer consisting of five radiation fractions of five Grays delivered over five days and surgery performed the following week. Advances in treatment regimens over the last few decades have improved survival rates of rectal cancer.
Keywords
rectal cancer; short-course radiotherapy; neoadjuvant therapy
Hrčak ID:
314275
URI
Publication date:
12.2.2024.
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