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Medica Jadertina, Vol. 54 No. 1, 2024.

Professional paper

https://doi.org/10.57140/mj.54.1.5

Pregnancy complicated by small cell neuroendocrine carcinoma of the cervix: a case presentation

Marko Vulić orcid id orcid.org/0000-0002-3198-4976 ; Split Clinical Hospital Centre, Department of gynaecology and Obstetrics; University of Split, School of Medicine
Branka Petrić Miše ; University of Split, School of Medicine; Split Clinical Hospital Centre, Department of Oncology
Sandra Zekić orcid id orcid.org/0000-0003-2964-5171 ; University of Split, School of Medicine; Split Clinical Hospital Centre, Department of Pathology
Damir Roje orcid id orcid.org/0000-0003-1557-9628 ; Split Clinical Hospital Centre, Department of Gynaecology and Obstetrics; University of Splt, School of Medicine; University of Split, Department of Health Studies
Marko Jukić ; Split Clinical Hospital Centre, Department of Gynaecology and Obstetrics; University of Split, School of Medicine
Dino Markovina ; Split Clinical Hospital Centre, Department of Gynaecology and Obstetrics; University of Split, School of M;edicine
Luka Vulić ; Sestre milosrdnice University Hospital Center, Zagreb, Department of Gynaecology and Obstetrics

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Abstract

Small cell neuroendocrine carcinoma of the cervix (SCNCC) is considered to be an extremely rare,
highly invasive and aggressive subtype of squamous cell carcinoma. It is particulary rare during pregnancy.
Here we report a case in which a 32-year-old patient who was admitted to our Department at 27 completed
weeks of gestation with intermittent vaginal spotting and a large amount of malodorous vaginal discharge.
Gynecological examination revealed a 2 cm exophytic polypoid tumor coming out of the cervix. On rectal
examination there was no clinically evident parametrial invasion. Biopsy of the cervix was performed and
the diagnosis of small cell neuroendocrine carcinoma was established. We reviewed and discussed the
features, diagnosis, treatment and prognosis of SCNCC diagnosed during pregnancy.

Keywords

pregnancy; small cell neuroendocrine carcinoma; cervix

Hrčak ID:

315739

URI

https://hrcak.srce.hr/315739

Publication date:

4.4.2024.

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