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Original scientific paper

https://doi.org/10.46419/vs.56.2.5

Assessment of Novel Haematological Inflammatory Markers (NLR, SII, and SIRI) as Predictors of SIRS in Dogs with Canine Monocytic Ehrlichiosis

Hasan Erdogan ; Faculty of Veterinary Medicine, Aydın Adnan Menderes University, Aydın, Turkey *
Tahir Ozalp ; Faculty of Veterinary Medicine, Aydın Adnan Menderes University, Aydın, Turkey
Songul Erdogan ; Faculty of Veterinary Medicine, Aydın Adnan Menderes University, Aydın, Turkey
Kerem Ural ; Faculty of Veterinary Medicine, Aydın Adnan Menderes University, Aydın, Turkey

* Corresponding author.


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Abstract

Canine monocytic ehrlichiosis (CME) is a tick-borne and fatal disease that induces a systemic inflammatory response syndrome (SIRS), which underscores the importance of assessing the level of inflammation. In this study, we aimed to evaluate changes in the SII and SIRI indexes in dogs with CME based on the presence of SIRS criteria. A total of 53 dogs affected with CME and 13 healthy dogs were included in the study. Haematological data, including neutrophil to lymphocyte ratio (NLR), systemic inflammatory index (SII), and systemic inflammatory response index (SIRI), were collected and statistically compared between groups based on SIRS status. The NLR and SIRI indexes were significantly higher in dogs with CME that meet the criteria for SIRS compared to dogs without SIRS and healthy controls. In summary, monitoring the SIRI index can aid in evaluating SIRS criteria in dogs with CME, which can help improve their treatment and overall prognosis.

Keywords

canine monocytic ehrlichiosis; neutrophil to lymphocyte ratio; systemic inflammatory index; systemic inflammatory response index

Hrčak ID:

319598

URI

https://hrcak.srce.hr/319598

Publication date:

14.8.2024.

Article data in other languages: croatian

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