Original scientific paper

https://doi.org/10.20471/acc.2023.62.04.14

Effects of Preoperative Anxiety, Depression and Pain on Quality of Postoperative Recovery and acute Postoperative Pain after Radical Prostatectomy: a Prospective Observational Study

Nina Sulen ; Department of Anesthesiology, Resuscitation and Intensive Care Medicine, Zadar General Hospital, Zadar, Croatia; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Health Studies, University of Zadar, Zadar, Croatia
Tatjana Šimurina orcid.org/0000-0002-2657-5537 ; Department of Anesthesiology, Resuscitation and Intensive Care Medicine, Zadar General Hospital, Zadar, Croatia; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Health Studies, University of Zadar, Zadar, Croatia *
Ivan Požgain ; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; Department of Psychiatry, Osijek University Hospital Center, Osijek, Croatia
Miroslav Župčić orcid.org/0000-0002-1989-7255 ; Department of Anesthesiology and Intensive Care Medicine, Rijeka University Hospital Center, Rijeka, Croatia; Faculty of Health Studies, University of Rijeka, Rijeka, Croatia
Tomislav Sorić ; Department of Health Studies, University of Zadar, Zadar, Croatia; Department of Urology, Zadar General Hospital, Zadar, Croatia
Eugenija Basioli Kasap orcid.org/0009-0006-1095-0634 ; Department of Health Studies, University of Zadar, Zadar, Croatia; Department of Pulmonology, Zadar General Hospital, Zadar, Croatia
Boris Mraović orcid.org/0000-0003-4019-4084 ; Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Missouri, Columbia, MO, USA

* Corresponding author.

Abstract

Patients with prostate cancer are often in psychological distress and pain preoperatively.
The aim of this study was to examine the effects of preoperative anxiety, depression and pain
on the quality of postoperative recovery and acute postoperative pain after radical prostatectomy. One
hundred and sixty patients scheduled for open or laparoscopic radical prostatectomy were enrolled in
a prospective observational study. Psychological distress was assessed with the State-Trait Anxiety Inventory
(STAI-S and STAI-T) and Center for Epidemiological Studies Depression Scale (CES-D).
Postoperative recovery was assessed on postoperative days 1-3 using the Quality of Recovery-40 score
(QoR-40). Numeric rating scale 0-10 was used to assess the intensity of postoperative pain at rest and
on movement at 1, 6 and 24 hours post-surgery. In linear regression models, STAI-S was predictor of
QoR-40 on postoperative days 1-3 (ß=-17.32; p<0,001, ß=-0.345; p=0.004, and ß=-0.326; p=0.002,
respectively), and preoperative pain was predictor of pain at rest (ß=0.666; p=0.008) and on movement
(ß=0.691; p=0.006). In logistic regression models, preoperative pain was predictor of clinically significant
pain at rest (OR, 2.86; 95% CI 1.11-7.36) and STAI-S of clinically significant pain on movement (OR,
2.21; 95% CI, 1.08-4.52). In conclusion, state anxiety had negative impact on QoR and acute pain after
radical prostatectomy. Preoperative pain was associated with acute postoperative pain.

Keywords

Anxiety; Depression; Pain; Postoperative recovery; Prostatectomy

Hrčak ID:

320304

URI

https://hrcak.srce.hr/320304

Publication date:

31.12.2023.

Article data in other languages: croatian

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