Veterinary Archives, Vol. 94 No. 6, 2024.
Original scientific paper
https://doi.org/10.24099/vet.arhiv.2515
Resistance of different types of nontuberculos mycobacteria to aldehyde disinfectants
Anatoliy Paliy
; National Scientific Center “Institute of Experimental and Clinical Veterinary Medicine”, Kharkiv, Ukraine
Andriy Zavgorodnii
; National Scientific Center “Institute of Experimental and Clinical Veterinary Medicine”, Kharkiv, Ukraine
Kateryna Rodionova
; Odesa State Agrarian University, Odesa, Ukraine
*
Sergii Borovkov
; National Scientific Center “Institute of Experimental and Clinical Veterinary Medicine”, Kharkiv, Ukraine
Olena Pavlichenko
; State Biotechnological University, Kharkiv, Ukraine
Ruslan Dubin
; Odesa State Agrarian University, Odesa, Ukraine
Tetiana Ihnatieva
; State Biotechnological University, Kharkiv, Ukraine
* Corresponding author.
Abstract
Nontuberculos mycobacteria (NTM) are widely distributed, and investigation of their ecology establishes а basis for the development of new agents and methods for their identification, differentiation and devitalization. This study aimed to evaluate the resistance of different types of NTM to aldehyde-containing disinfectants with different concentrations of active ingredients. The experiments employed complex disinfectants with glutaraldehyde as the active ingredient. Test cultures of several types of NTM belonging to groups I (M. kansasii), II (M. gordonae, M. scrofulaceum), III (M. intracellulare, M. terrae, M. triviale, M. xenopi) and IV (M. diernhoferi, M. flavescens, M. fortuitum, M. phlei, M. smegmatis, M. thamnopheos) according to the Runyon classification, were used. The research confirmed that NTM of different species and strains show different resistance to the same disinfectant. The mycobacteria species M. fortuitum, M. intracellulare, M. scrofulaceum, and M. thamnopheos displayed the highest resistance to aldehyde-containing disinfectants. The effectiveness of an antimicrobial agent against mycobacteria depends on the concentration of the active ingredient and the duration of exposure. Future research should be focused on examining variations in the resistance of mycobacteria to new disinfectants from different chemical categories.
Keywords
disinfectant; nontuberculos mycobacteria (NTM); resistance; bactericidal effect; concentration; exposure
Hrčak ID:
322081
URI
Publication date:
1.11.2024.
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