Book review

https://doi.org/10.20471/acc.2024.63.01.23

Osteosarcoma in a patient with cranial fibrous dysplasia: a case report

Danko Müller ; Department of Pathology, Dubrava University Hospital, Zagreb, Croatia; Department of Pathology, School of Medicine, University of Zagreb, Zagreb, Croatia *
Naranđa Aljinović Ratković ; Department of Maxillofacial Surgery, Dubrava University Hospital, Zagreb, Croatia
Igor Blivajs ; Department of Maxillofacial Surgery, Dubrava University Hospital, Zagreb, Croatia
Dalibor Franćeski ; Department of Radiology, Dubrava University Hospital, Zagreb, Croatia
Karolina Krstanac ; Department of Pathology, Dubrava University Hospital, Zagreb, Croatia
Sven Seiwerth ; Department of Pathology, School of Medicine, University of Zagreb, Zagreb, Croatia

* Corresponding author.

Abstract

Fibrous dysplasia is a benign fibro-osseous lesion which rarely undergoes malignant
transformation, frequently after radiotherapy. Osteosarcoma is the most common malignancy arising
in fibrous dysplasia. We report a case of 67-year-old female patient with osteosarcoma developing in
long lasting fibrous dysplasia without prior radiation. The patient underwent surgery with postoperative
chemotherapy. She developed two relapses over the course of four years after the initial therapy. With
this case, we want to underline the importance of noticing any significant change in the otherwise
unremarkable course in patients with fibrous dysplasia.

Keywords

Fibrous dysplasia; Malignant transformation; Osteosarcoma; Radiotherapy

Hrčak ID:

322707

URI

https://hrcak.srce.hr/322707

Publication date:

1.4.2024.

Article data in other languages: croatian

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