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Cardiologia Croatica, Vol. 19 No. 11-12, 2024.

Meeting abstract

https://doi.org/10.15836/ccar2024.407

Survival benefits of an implantable cardioverter-defibrillator implantation: comparing outcomes in ischemic and non-ischemic cardiomyopathy – single centre experience

Mislav Puljević orcid id orcid.org/0000-0003-1477-2581 ; University of Zagreb, School of Medicine, Zagreb, Croatia
Mia Dubravčić Došen orcid id orcid.org/0000-0003-0441-4772 ; University Hospital Centre Zagreb, Zagreb, Croatia
Vedran Pašara orcid id orcid.org/0000-0002-6587-2315 ; University Hospital Centre Zagreb, Zagreb, Croatia
Ivan Prepolec ; University Hospital Centre Zagreb, Zagreb, Croatia
Pero Hrabač orcid id orcid.org/0000-0001-7382-4789 ; University of Zagreb, School of Medicine, Zagreb, Croatia
Ana-Marija Brekalo orcid id orcid.org/0000-0003-0053-0442 ; University Hospital Centre Zagreb, Zagreb, Croatia
Martina Lovrić-Benčić orcid id orcid.org/0000-0001-8446-6120 ; University of Zagreb, School of Medicine, Zagreb, Croatia
Miroslav Krpan ; University Hospital Centre Zagreb, Zagreb, Croatia
Richard Matasić orcid id orcid.org/0000-0003-1289-1704 ; University Hospital Centre Zagreb, Zagreb, Croatia
Borka Pezo Nikolić orcid id orcid.org/0000-0002-0504-5238 ; University Hospital Centre Zagreb, Zagreb, Croatia
Davor Puljević orcid id orcid.org/0000-0003-3603-2242 ; University of Zagreb, School of Medicine, Zagreb, Croatia
Davor Miličić orcid id orcid.org/0000-0001-9101-1570 ; University of Zagreb, School of Medicine, Zagreb, Croatia
Vedran Velagić orcid id orcid.org/0000-0001-5425-5840 ; University of Zagreb, School of Medicine, Zagreb, Croatia

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Abstract

Keywords

implantable cardioverter-defibrillator; sudden cardiac death; non-ischemic cardiomyopathy; ischemic cardiomyopathy

Hrčak ID:

327852

URI

https://hrcak.srce.hr/327852

Publication date:

13.12.2024.

Visits: 314 *

Copyright statement: Croatian Cardiac Society

Copyright: 2024, Croatian Cardiac Society

Date received: 24 September 2024

Date: 31 October 2024

Publication date: November 2024

Publication date: November 2024

Volume: 19

Issue: 11-12

Page: 407

Publisher ID: CC 2024 19_11-12_407

DOI: 10.15836/ccar2024.407

Article Information (continued)

Categories:

Subject: Extended Abstract

Categories:

Subject: Arrhythmology and electrostimulation

KEYWORDS: :

KEYWORDS:

Keyword: implantable cardioverter-defibrillator

Keyword: sudden cardiac death

Keyword: non-ischemic cardiomyopathy

Keyword: ischemic cardiomyopathy

Survival benefits of an implantable cardioverter-defibrillator implantation: comparing outcomes in ischemic and non-ischemic cardiomyopathy – single centre experience

[https://orcid.org/0000-0003-1477-2581] Mislav Puljević[1][2][*]

[https://orcid.org/0000-0003-0441-4772] Mia Dubravčić Došen[2]

[https://orcid.org/0000-0002-6587-2315] Vedran Pašara[2]

[https://orcid.org/0000-0001-5870-202X] Ivan Prepolec[2]

[https://orcid.org/0000-0001-7382-4789] Pero Hrabač[1]

[https://orcid.org/0000-0003-0053-0442] Ana-Marija Brekalo[2]

[https://orcid.org/0000-0001-8446-6120] Martina Lovrić-Benčić[1][2]

[https://orcid.org/0000-0002-0639-953X] Miroslav Krpan[2]

[https://orcid.org/0000-0003-1289-1704] Richard Matasić[2]

[https://orcid.org/0000-0002-0504-5238] Borka Pezo Nikolić[2]

[https://orcid.org/0000-0003-3603-2242] Davor Puljević[1][2]

[https://orcid.org/0000-0001-9101-1570] Davor Miličić[1][2]

[https://orcid.org/0000-0001-5425-5840] Vedran Velagić[1][2]

 

[1] University of Zagreb, School of Medicine, Zagreb, Croatia

[2] University Hospital Centre Zagreb, Zagreb, Croatia

Author notes:

Correspondence to: [*] ADDRESS FOR CORRESPONDENCE: Mislav Puljević, Klinički bolnički centar Zagreb, Kišpatićeva 12, HR-10000 Zagreb, Croatia. / Phone: +385-91-4680-414 / E-mail: puljevicmislav@gmail.com

Introduction: While implantable cardioverter-defibrillators (ICD) effectively reduce sudden cardiac death, their impact on overall survival differs between ischemic cardiomyopathy (ICM) and non-ischemic cardiomyopathy (NICM). (1-3) This study investigates survival outcomes and the significance of age in a cohort of ICD recipients.

Patients and Methods: A retrospective cohort of 786 patients who underwent ICD implantation between 2009 and 2018 was analyzed. Survival outcomes were assessed with a focus on differences between ICM and NICM, and the influence of age on device efficacy.

Results: Patients with NICM showed a lower rate of appropriate device activation compared to ICM (23% vs. 28%). Despite this, ICD implantation significantly improved survival in both groups, with younger patients (<70 years) benefiting the most. Age, non-sustained ventricular tachycardia (NSVT), and cardiac decompensation history were strong predictors of (non)survival.

Conclusions: ICD implantation offers clear survival benefits in both ICM and NICM, though younger patients and those with ischemic cardiomyopathy experience better outcomes. Age and cardiomyopathy type are crucial factors in determining the effectiveness of ICD therapy.

LITERATURE

1 

Theuns DA, Verstraelen TE, van der Lingen ACJ, Delnoy PP, Allaart CP, van Erven L, et al. Implantable defibrillator therapy and mortality in patients with non-ischaemic dilated cardiomyopathy: An updated meta-analysis and effect on Dutch clinical practice by the Task Force of the Dutch Society of Cardiology. Neth Heart J. 2023 March;31(3):89–99. https://doi.org/10.1007/s12471-022-01718-3 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/36066840

2 

Elming MB, Nielsen JC, Haarbo J, Videbæk L, Korup E, Signorovitch J, et al. Age and Outcomes of Primary Prevention Implantable Cardioverter-Defibrillators in Patients With Nonischemic Systolic Heart Failure. Circulation. 2017 November 7;136(19):1772–80. https://doi.org/10.1161/CIRCULATIONAHA.117.028829 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/28877914

3 

Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA, et al. ESC Scientific Document Group. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022 October 21;43(40):3997–4126. https://doi.org/10.1093/eurheartj/ehac262 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/36017572

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