Original scientific paper

https://doi.org/10.20471/acc.2024.63.02.13

Arteriovenous fistula for hemodialysis in relation to the timing of creation: analysis of key factors

Radojica V. Stolić orcid.org/0000-0002-6215-9258 ; University of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, Serbia *
Mirjana Pajčin ; University of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, Serbia
Vekoslav Mitrović ; University of East Sarajevo, Faculty of Medicine, Republika Srpska, Foča, Bosnia and Herzegovina
Nataša D. Zdravković ; University of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, Serbia
Saša Sovtić= ; University of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, Serbia
Snežana Marković-Jovanović ; University of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, Serbia
Slavica Pajović ; University of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, Serbia
Kristina Bulatović ; University of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, Serbia
Branka Mitić ; University of Niš, Faculty of Medicine, Niš, Serbia
Dragiša Rašić ; University of Pristina/Kosovska Mitrovica, Faculty of Medicine, Pristina/Kosovska Mitrovica, Serbia

* Corresponding author.

Abstract

Timely creation of an arteriovenous fistula is not always feasible. The aim was to
determine the key factors for functionality and maturation of arteriovenous fistulas in relation to timing
of its creation. The research was conducted at the Department of Nephrology and Dialysis, Kragujevac
University Clinical Center, Kragujevac, Serbia, in patients who had had a fistula surgically created
over a period of fifteen years. A total of 1089 patients were registered. All clinical and biochemical
parameters that were of interest for this study were analyzed. The group of patients with fistulas created
before the start of hemodialysis was statistically different from the group of patients whose fistulas
were created after the start of hemodialysis according to vein lumen (p=0.005), systolic blood pressure
(p<0.001), total cholesterol (p<0.001), HDL cholesterol (p=0.008) and LDL cholesterol (p<0.001).
Predictive parameters of the initial dysfunction were vein diameter (p=0.004), cholesterol (p=0.008)
and LDL cholesterol (p=0.033), while the maturation parameter was systolic blood pressure (p=0.042).
In conclusion, predictive parameters of initial fistula dysfunction are vein diameter, cholesterol and
LDL cholesterol, while systolic blood pressure is most important for maturation.

Keywords

Predictive parameters; Initial function; Maturation; Arteriovenous fistula; Timing of creation

Hrčak ID:

327962

URI

https://hrcak.srce.hr/327962

Publication date:

31.10.2025.

Article data in other languages: croatian

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