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Meeting abstract

https://doi.org/10.15836/ccar2025.108

Echocardiographic Predictors of Atrial Fibrillation Recurrence After Ablation: Insights from University Hospital Centre Zagreb

Iva Golubić orcid id orcid.org/0009-0008-2495-5676 ; Special Hospital for Medical Rehabilitation Krapinske Toplice, Krapinske Toplice, Croatia
Antun Zvonimir Kovač orcid id orcid.org/0000-0001-6276-4450 ; University Hospital Centre Zagreb, Zagreb, Croatia
Sandra Jakšić Jurinjak orcid id orcid.org/0000-0002-7349-6137 ; University Hospital Centre Zagreb, Zagreb, Croatia
Marija Brestovac orcid id orcid.org/0000-0003-1542-2890 ; University Hospital Centre Zagreb, Zagreb, Croatia
Vedran Velagić orcid id orcid.org/0000-0001-5425-5840 ; University Hospital Centre Zagreb, Zagreb, Croatia
Ivan Prepolec ; University Hospital Centre Zagreb, Zagreb, Croatia
Andrija Nekić orcid id orcid.org/0000-0003-1214-8646 ; University Hospital Centre Zagreb, Zagreb, Croatia
Vedran Pašara orcid id orcid.org/0000-0002-6587-2315 ; University Hospital Centre Zagreb, Zagreb, Croatia
Vlatka Rešković Lukšić orcid id orcid.org/0000-0002-4721-3236 ; University Hospital Centre Zagreb, Zagreb, Croatia


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Abstract

Keywords

atrial fibrillation; echocardiography; catheter ablation

Hrčak ID:

330603

URI

https://hrcak.srce.hr/330603

Publication date:

5.5.2025.

Visits: 427 *



Introduction: Echocardiographic measurements, such as left atrial (LA) volume, strain, and diastolic dysfunction, have been identified as valuable predictors of atrial fibrillation (AF) recurrence after ablation (1,2). These factors are associated with structural remodelling, including atrial myocardial fibrosis, which may contribute to an increased likelihood of recurrence (3). In this study, we aimed to evaluate echocardiographic predictors of AF recurrence in our patient population.

Patients and Methods: We conducted a retrospective analysis of patients who underwent AF ablation between February 2022 and September 2024. AF recurrence during follow-up up was recorded. Data comparison between patients with and without recurrence was performed using t-tests and chi-square.

Results: A total of 39 patients with preprocedural echocardiography examination available for further analysis were identified and included in the analysis. Baseline characteristics, laboratory findings, and echocardiographic measurements are summarized inTable 1. Statistical analysis revealed a significant difference between the recurrence and non-recurrence groups in LA reservoir strain (p=0.002) and E/e’ ratio (p<0.001).

TABLE 1 Statistical analysis of echocardiographic measurements.
No recurrenceAF recurrencep value
Age63.83±8.4368.27±9.570.138
Female10 (41.7%)7 (46.7%)0.759
NTproBNP125.75±80.831222.17±2493.770.142
Diastolic dysfunctionGrade 0 = 4 (16.7%)
Grade 1 = 16 (66.7%)
Grade 2 = 4 (16.7%)
Grade 0 = 0 (0.0%)
Grade 1 = 8 (53.3%)
Grade 2 = 7 (46.7%)
0.057
LAVI34.38±7.7938.07±9.680.198
LA strain26.58±5.3019.33±8.230.002
RAV33.08±9.9837.13±9.930.224
RAA14.13±2.7414.93±2.520.362
sPAP21.71±6.9223.54±8.410.519
Deceleration time268.13±83.38236.40±79.460.247
E/A1.03±0.401.61±0.510.381
IVRT101.46±24.98105.93±32.770.632
E/e’6.75±1.829.60±2.32<0.001
Total24 (61.5%)15 (38.5%)
LAVI - left atrium indexed volume, LA – left atrium, RAV - right atrium volume, RAA- right atrium area, sPAP - systolic pulmonary artery pressure, E/A - transmitral E wave and A wave ratio, IVRT - isovolumic relaxation time, E/e’ - peak early diastolic velocity of mitral inflow and mitral annular motion ratio

Conclusion: Although our study is limited by a small sample size, the findings align with previous research, suggesting that LA strain and E/e’ ratio may serve as valuable predictors of atrial fibrillation recurrence. Future studies with larger cohorts are needed to confirm these results and integrate these echocardiographic parameters into clinical management strategies.

LITERATURE

1 

Liżewska-Springer A, Dąbrowska-Kugacka A, Lewicka E, Drelich Ł, Królak T, Raczak G. Echocardiographic predictors of atrial fibrillation recurrence after catheter ablation: A literature review. Cardiol J. 2020;27(6):848–56. https://doi.org/10.5603/CJ.a2018.0067 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/29924375

2 

Karanikola AE, Tzortzi M, Kordalis A, Doundoulakis I, Antoniou CK, Laina A, et al. Clinical, Electrocardiographic and Echocardiographic Predictors of Atrial Fibrillation Recurrence After Pulmonary Vein Isolation. J Clin Med. 2025 January 26;14(3):809. https://doi.org/10.3390/jcm14030809 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/39941478

3 

Hopman LHGA, Mulder MJ, van der Laan AM, Demirkiran A, Bhagirath P, van Rossum AC, et al. Impaired left atrial reservoir and conduit strain in patients with atrial fibrillation and extensive left atrial fibrosis. J Cardiovasc Magn Reson. 2021 November 11;23(1):131. https://doi.org/10.1186/s12968-021-00820-6 PubMed: http://www.ncbi.nlm.nih.gov/pubmed/34758820


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