Original scientific paper
https://doi.org/10.20471/acc.2024.63.03-04.38
Mild Cognitive Impairment and Cardiometabolic Risk Factors in Bosnian and Herzegovinian Patients with Heart Failure
Jasna Ibrahimović-Pašić
orcid.org/0000-0003-3165-3760
; Department of General Internal Medicine and Gastroenterology, Prim. Dr. Abdulah Nakaš General Hospital, Sarajevo, Bosnia and Herzegovina
Orhan Lepara
; University of Sarajevo, Faculty of Medicine, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina
Amela Dervišević
orcid.org/0000-0002-4251-1437
; University of Sarajevo, Faculty of Medicine, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina
Nermina Babić
orcid.org/0000-0002-3207-0172
; University of Sarajevo, Faculty of Medicine, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina
Nesina Avdagić
orcid.org/0000-0003-4089-3037
; University of Sarajevo, Faculty of Medicine, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina
Amina Valjevac
; University of Sarajevo, Faculty of Medicine, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina
Asija Začiragić
orcid.org/0000-0002-3293-4698
; University of Sarajevo, Faculty of Medicine, Department of Human Physiology, Sarajevo, Bosnia and Herzegovina
*
* Corresponding author.
Abstract
The aim of the present study was to assess mild cognitive impairment (MCI)
and cardiometabolic risk factors (CMRF) in Bosnian and Herzegovinian patients with heart failure
(HF). This study included 80 patients with HF and 40 healthy controls. Montreal Cognitive Assessment
(MoCA) testing was used to evaluate cognitive function. Abdominal obesity was assessed by waist
circumference, and hypertension was assessed by the auscultatory method. Data on other CMRF and
comorbidities, such as diabetes, smoking, alcohol consumption, and atrial fibrillation (AF), were gathered
with a specially designed questionnaire. Lipids, C-reactive protein (CRP), and fibrinogen were
assessed with standard laboratory methods. Student, Mann-Whitney, and Chi-square tests were used to
determine significant differences between groups. Associations between categorical variables and correlation
coefficients were assessed by the Chi-square and Spearman test, respectively. The prevalence of
MCI in patients with HF was 77.5%. We found significant associations between MCI and diabetes,
hypertension, AF, and smoking in patients with HF. We found no significant associations between MCI,
abdominal obesity, and alcohol consumption. A significant positive correlation between MCI and total
cholesterol was observed in patients with HF. Furthermore, a lower MoCA score was associated with
higher values of CRP and fibrinogen in HF patients. The present study showed a high prevalence of
MCI in Bosnian and Herzegovinian HF patients as well as its association with various CMRFs. These
results suggest it is necessary to begin MCI screening in HF patients, especially since data from the literature
point to improvement in cognitive performance with appropriate HF and concomitant CMRF
treatment.
Keywords
Mild cognitive impairment; Cardiometabolic risk factors; Heart failure
Hrčak ID:
333342
URI
Publication date:
31.12.2024.
Visits: 765 *