Book review
https://doi.org/10.20471/acc.2024.63.03-04.45
Pheochromocytoma Crisis Treated with Urapidil: a Case Report
Miro Bakula
; Sveti Duh University Hospital, Division of Endocrinology, Department of Internal Medicine, Zagreb, Croatia
*
Lea Tomašić
; graduate student, School of Medicine, University of Zagreb, Zagreb, Croatia
Ivana Kokan
; graduate student, School of Medicine, University of Zagreb, Zagreb, Croatia
Katarina Mucić
; graduate student, School of Medicine, University of Zagreb, Zagreb, Croatia
Nikolina Marić
; Sveti Duh University Hospital, Department of Intensive Care, Zagreb, Croatia
Maja Bakula
; Merkur University Hospital, University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Zagreb, Croatia
* Corresponding author.
Abstract
Pheochromocytomas are rare tumors that present with a broad spectrum of symptoms
and signs, making differential diagnosis broad. They can cause a pheochromocytoma crisis that
manifests with arterial blood pressure oscillations, and subsequent symptoms and signs of catecholamine
overproduction. There are many potential triggers of this condition. This report presents a 33-year-old
man with an obvious pheochromocytoma crisis that occurred due to beta-blocker application without
a concomitant alpha-blocker. The crisis was treated with high doses of urapidil, and once permanent
hemodynamic stabilization was achieved, urapidil was replaced with phenoxybenzamine. This report
demonstrates that pheochromocytoma crisis can be successfully treated with urapidil but further consideration
is needed on the use of urapidil both in pheochromocytoma crisis and preoperative management
of pheochromocytoma patients.
Keywords
Pheochromocytoma; Hypertensive crisis; Urapidil
Hrčak ID:
333369
URI
Publication date:
31.12.2024.
Visits: 1.123 *