Review article
https://doi.org/10.3325/cmj.2025.66.289
The effect of sleep-oriented non-pharmacological interventions in preventing delirium: a systematic review of randomized controlled trials
Ezgi Mutluay Yayla
; Nursing Department, Health Sciences Faculty, Tarsus University, Tarsus, Turkey
*
Emine Kaplan Serin
; Department of Medical Nursing, Faculty of Nursing, Mersin University, Mersin, Turkey
* Corresponding author.
Abstract
Aim To systematically review randomized controlled trials
evaluating the efficacy of sleep-oriented non-pharmaco
logical interventions for delirium prevention in intensive
care units.
Methods We searched PubMed, Web of Science, Scopus,
and the Cochrane Library for randomized controlled trials
evaluating the efficacy of sleep-oriented, non-pharmaco
logical interventions for delirium prevention in intensive
care units published in English between 2019 and 2024.
The methodological quality of the included studies was in
dependently evaluated by two researchers using the Jo
anna Briggs Institute tool.
Results This review included eight randomized controlled
trials (n = 649). Six studies assessed the effect of earplugs
and masks on delirium prevention in intensive care pa
tients. Three studies indicated that earplugs and eye masks
effectively prevented delirium, while three studies found
no effect. One study assessed the use of earplugs and
masks as part of a bundle of interventions and reported
a positive effect. Four studies showed an effect on sleep.
None of the sleep-oriented non-pharmacological inter
ventions assessed in these studies reported any harmful
effects.
Conclusion Although several high-quality studies showed
that these interventions significantly lowered delirium inci
dence, some trials found no effect, highlighting variability
in outcomes
Keywords
Hrčak ID:
352539
URI
Publication date:
31.8.2025.
Visits: 0 *