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Haemodynamic effects and the visibility of the surgical field after lidocaine infiltration during septoplasty under general anaesthesia

TATJANA GORANOVIĆ ; Department of Anaesthesia and Intensive Care Unit, General Hospital Sveti Duh, Sveti Duh 64, 10000 Zagreb, Croatia
MORENA MILIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care Medicine, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, Croatia
DOMAGOJ PARAZAJDER ; Department of Otorhinolaryngology, General Hospital Sveti Duh, Sveti Duh 64, 10000 Zagreb, Croatia
ESAD AVDAGIĆ ; Department of Otorhinolaryngology, General Hospital Sveti Duh, Sveti Duh 64, 10000 Zagreb, Croatia
DENIS NENADIĆ ; Department of Surgery, University Clinical Centre Split, Spinčićeva 1, 21000 Split, Croatia
BRANIMIR VUČKOVIĆ ; Department of Surgery, General Hospital Sveti Duh, Sveti Duh 64, 10000 Zagreb, Croatia
BRANKA MALDINI1 ; Department of Anaesthesia and Intensive Care Unit, General Hospital Sveti Duh, Sveti Duh 64, 10000 Zagreb, Croatia
KATARINA ŠAKIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care Medicine, University Clinical Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia

Abstract

Background and Purpose: The aim of this study was to determine the
effect of local infiltration of adrenaline- containing lidocaine solution during septoplasty under general anaesthesia on systemic haemodynamics and the visibility of the operative field, and to compare it to the topical application of ephedrine.

Patients and Methods: A retrospective, comparative, non-randomised,
open study on 72 ASA physical status I and II patients, aged 20 to 73 years, scheduled for septoplasty was performed. Lidocaine/adrenaline-ephedrine group (group LA-E; n=18) received four cotton pledgets soaked with 1 % ephedrine, and then the submucosal infiltration of 2% lidocaine containing adrenaline solution (2ml) plus plain 2% lidocaine solution (5ml). Lidocaine/
adrenaline group (LA group; n=25) received the submucosal infiltration of 2% lidocaine containing adrenaline solution (2ml) plus plain 2% lidocaine solution (5ml). Ephedrine group (E group; n=29) received four cotton pledgets soaked with 1% ephedrine. Heart rate (HR) and mean arterial pressure (MAP) were recorded at predetermined time intervals. Bleeding in the surgical field was rated according to a 6-point scale.

Results: LA and LA-E groups showed significant lower HR and MAP
compared to E-group. LA group showed only slight oscillations in HR. Average bleeding score was 2.28±0.83 in LA-E, 2.08±0.81 in LA and
3.14±0.74 in E group (p<0.001).

Conclusions:We demonstrated that infiltration of lidocaine with adrenaline has statistically and clinically better impact on systemic haemodynamics and visibility of the surgical field than that achieved by topical application
of ephedrine alone.

Keywords

Anesthesia; general; Anesthesia; local; Lidocaine; Adrenaline; Nasal septum; Surgical procedures; Ephedrine

Hrčak ID:

38242

URI

https://hrcak.srce.hr/38242

Publication date:

15.6.2009.

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