Original scientific paper

COMPARATIVE ANALYSIS OF SOFT NEUROLOGICAL SIGNS IN POSITIVE AND NEGATIVE SUBTYPE OF SCHIZOPHRENIA

Tijana Cvetić ; Institute of Psychiatry, Clinical Center of Serbia, Belgrade, Serbia
Olivera Vuković ; Institute of Psychiatry, Clinical Center of Serbia, Belgrade, Serbia
Dubravka Britvić ; Institute of Psychiatry, Clinical Center of Serbia, Belgrade, Serbia
Maja Ivković ; Institute of Psychiatry, Clinical Center of Serbia, Belgrade, Serbia
Slavica Đukić-Dejanović ; Institute of Psychiatry, Clinical Centre of Kragujevac, Kragujevac, Serbia
Dušica Lečić-Toševski ; Institute of Mental Health, Belgrade, Serbia

Abstract

Background: The objective of the study was to investigate neurological deficit in schizophrenia and to compare soft neurological signs in positive and negative subtypes of schizophrenia.
Subjects and methods: 66 patients with schizophrenia were evaluated with the
Positive and Negative Syndrome Scale to classify the subtype of schizophrenia: positive subtype (36 patients) and negative subtype (30 patients), all of which were entering into remission. To examine the neurological soft signs we compared scores on the Neurological Evaluation Scale (NES) for positive and negative subtype.
Results: The negative subtype of schizophrenia showed significantly higher neurological soft signs in comparison to the positive subtype, with reduced functioning in the sensory integration and motor coordination subscale as well as the other subscale.
Conclusion: The main finding in this study indicates that patients with
schizophrenia have neurological impairment, and that the negative subtype has significantly higher neurological impairment than the positive subtype. The results further support the significance of the soft neurological signs as a possible marker of different subtypes of schizophrenia.

Keywords

Schizophrenia; positive/negative subtype; neurological soft signs

Hrčak ID:

39643

URI

https://hrcak.srce.hr/39643

Publication date:

21.3.2009.

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