Short communication, Note

https://doi.org/10.2478/v10007-009-0034-7

An improved procedure for synthesis of some new 1,3-diaryl-2-propen-1-ones using PEG-400 as a recyclable solvent and their antimicrobial evaluation

BHASKAR S. DAWANE ; Organic Research Laboratory, Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S) India
SHANKARAIAH G. KONDA ; Organic Research Laboratory, Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S) India
BASEER M. SHAIKH ; Organic Research Laboratory, Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S) India
RAGHUNATH B. BHOSALE ; Organic Research Laboratory, Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S) India

Abstract

A simple and convenient route is described for the synthesis of novel hetero 1,3-diaryl-2-propen-1-ones (chalcones) by using recyclable poly PEG-400 as an alternative reaction solvent. The reaction is clean with excellent yield, shorter reaction time and reduces the use of volatile organic compounds (VOCs). All the synthesized compounds were evaluated for their antimicrobial activities against several pathogenic representatives.

Keywords

1,3-diaryl-2-propen-1-ones; PEG-400; antimicrobial activity

Hrčak ID:

40498

URI

https://hrcak.srce.hr/40498

Publication date:

1.12.2009.

Article data in other languages: croatian

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