Original scientific paper
Genetic Polymorphisms of 17 Y-chromosomal Short Tandem Repeat Loci in Atayal Population of Taiwan
Fang-Chin Wu
; Department of Forensic Science, Investigation Bureau, Ministry of Justice, Taipei County, Taiwan, R.O.C.
Chin-Wen Ho
; Department of Bioengineering, Tatung University, Taipei City, Taiwan, R.O.C.
Chang-En Pu
; Department of Forensic Science, Investigation Bureau, Ministry of Justice, Taipei County, Taiwan, R.O.C.
Kuang-Yu Hu
; Department of Biochemistry, National Defense Medical Center, Taipei City, Taiwan, R.O.C.
David Hwang Liu
; Department of Forensic Science, Investigation Bureau, Ministry of Justice, Taipei County, Taiwan, R.O.C.
Abstract
Aim To define the Y-chromosomal genetic structure in a
sample of Atayal men from Taiwan.
Methods Buccal swab samples were collected from 170
unrelated healthy male volunteers from Taiwanese aboriginal
Atayal population. Genomic DNA was extracted and 17
Y chromosome-specific short tandem repeat loci (DYS456,
DYS389I, DYS390, DYS389II, DYS458, DYS19, DYS385a/b,
DYS393, DYS391, DYS439, DYS635, DYS392, Y GATA H4,
DYS437, DYS438, and DYS448) were analyzed using the
AmpFlSTR Yfiler Polymerase Chain Reaction Amplification
Kit.
Results A total of 99 different haplotypes were identified,
69 (69.7%) of which were unique. Total haplotype diversity
was 0.9887. The most common haplotype was shared by
9 individuals in the study sample. Gene diversities ranged
from 0.0574 for DYS438 to 0.6749 for DYS456.
Conclusion Our results will help provide the molecular
genetic evidence for human settlement of the Pacific.
Keywords
Atayal; Y chromosome; haplotype; Y-STR; DYS19; Yfiler; Taiwan; Polynesian
Hrčak ID:
40691
URI
Publication date:
15.6.2009.
Visits: 1.347 *