Acta Pharmaceutica, Vol. 59 No. 4, 2009.
Short communication, Note
https://doi.org/10.2478/v10007-009-0036-5
Chemical composition of endemic Centaurea austro-anatolica and studies of its antimicrobial activity against multi-resistant bacteria
AYSEL UGUR
; Department of Biology, Faculty of Arts and Sciences, Mugla University, 48121 Kotekli-Mugla, Turkey
NURDAN SARAC
; Medical Laboratory Program, Vocational School of Health Services, Mugla University, 48700 Marmaris-Mugla, Turkey
OZGUR CEYLAN
; Department of Nursing, Health College, Usak University, 64100 Usak, Turkey
M. EMIN DURU
; Department of Chemistry, Faculty of Arts and Sciences, Mugla University, 48121 Kotekli-Mugla, Turkey
Abstract
Hexane, chloroform, ethyl acetate and ethanolic extracts of the aerial parts of C. austro-anatolica Hub.-Mor. (Asteraceae) were evaluated against microorganisms, including multi-resistant bacteria, using a paper disc diffusion method. The chloroform extract exhibited significant antibacterial activity toward all bacteria tested. The chemical composition of the chloroform extract was determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The major compounds of the extract were caryophyllene oxide (21.32 %), spathulenol (10.86 %), n-tricosanol (9.58 %) and geranyl isovalerate (8.71 %).
Keywords
Centaurea austro-anatolica (Asteraceae); chemical composition; antimicrobial activity
Hrčak ID:
40743
URI
Publication date:
1.12.2009.
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