Review article
Neuropathic pain
Vanja Bašić Kes
; Department od neurology, University hospital, Sestre milosrdnice, Zagreb, Croatia
Mira Ivanković
; Department of neurology, General hospital, Dubrovnik, Croatia
Milan Bitunjac
; Department of neurology, General hospital, Slavonski Brod, Croatia
Valbona Govori
; Department of neurology, University Clinical Centar, Pristhina, Kosovo
Vida Demarin
; Department od neurology, University hospital, Sestre milosrdnice, Zagreb, Croatia
Abstract
Neuropathic pain refers to pain that orginates from pathology of the nervous system. Common causes of neuropathic pain are diabetes mellitus, reactivation of herpes zoster, nerve compression or radiculopathy, alcohol, chemotherapy or abuse of some drugs and trigeminal neuralgia. Specific symptoms of neuropathic pain are mechanical allodynia and cold hyperlgesia. Drugs to treat neuropathic pain can be divided into adjuvent analgesics (antidepressants and anticonvulsants), opioids and topical agents. The use of multiple drug therapies is common in practice. Despite considerable increase in the number of randomized placebo-controlled trials in neuropathic pain over the last few years, the medical treatment of neuropathic pain is still far from being satisfactory, with kless than half of patients achieving signifi- cant benefit with any pharmacological drug.
Keywords
neuropathic pain; etiology; treatement
Hrčak ID:
42383
URI
Publication date:
20.10.2009.
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