Original scientific paper
Aging of Human Skeletal Muscles
Marina Nikolić
Snježana Bajek
Dragica Bobinac
Tamara Šoić Vranić
Romana Jerković
Abstract
Normal aging in humans is associated with progressive decrease in skeletal muscle mass and strength (sarcopenia) which contributes to frailty and falls. The age associated changes in body composition result from lower levels of anabolic hormones, oxidative damage, neuromuscular alterations and a general decrease in muscle protein turnover. In this review we discuss the potential mechanisms and physical activity as prevention and treatment of sarcopenia.
Keywords
Hrčak ID:
4939
URI
Publication date:
15.6.2005.
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