Conference paper

PHARMACOLOGIC SIDE EFFECTS AND/OR NEUROLOGIC DISORDER: CASE REPORT

Ljiljana Radanović-Grgurić ; University Department of Psychiatry, University Hospital Osijek, Osijek, Croatia
Anamarija Petek ; University Department of Psychiatry, University Hospital Osijek, Osijek, Croatia
Davor Laufer ; University Department of Psychiatry, University Hospital Osijek, Osijek, Croatia
Oliver Koić ; University Department of Psychiatry, University Hospital Osijek, Osijek, Croatia
Branko Radanović ; University Department of Neurology, University Hospital Osijek, Osijek, Croatia
Pavo Filaković ; University Department of Psychiatry, University Hospital Osijek, Osijek, Croatia

Abstract

The authors presented a patient with schizophrenia and with early parallel development of neurologic symptoms. At first, symptoms were manifested by extrapyramidal syndrome due to appliance of typical neuroleptics. Therefore, therapeutic approach was diverted to implementation of atipycal antiypsychotics.
Consequently patient developed orofacial diskyinesias which progrediated in unilateral choreo-atetoid movements. This followed two hospitalizations for diagnostic workup and correction of therapy. Only repeated brain MR showed moderate cortical atrophy. However, even with different therapeutic changes and approaches, we were not able to reach any significant shift neither in psychiatric
nor neurologic disturbances. The resistence on pharmacologic threapy led to suspicion of parallel development of neurologic disorder in form of Huntington chorea. Still remains the question whether primary neurologic disorder provoked psychotic process or there were two separate disorders where pharmacologic
intervention accelerated expansion of neurologic disorder.

Keywords

schizophrenia, antipsychotics side effects; neurologic disorder

Hrčak ID:

49635

URI

https://hrcak.srce.hr/49635

Publication date:

25.8.2009.

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