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Acta Pharmaceutica, Vol. 60 No. 3, 2010.

Short communication, Note

https://doi.org/10.2478/v10007-010-0030-y

Antioxidant properties of methanolic extracts of the leaves of seven Egyptian Cassia species

MAHER MAHMOUD EL-HASHASH ; Chemistry Department, Faculty of Science, Ain Shams University, Egypt
MAHFOUZ MOHAMED ABDEL-GAWAD ; Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Warrak El-Hader, Giza, Egypt
MORTADA MOHAMED EL-SAYED ; Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Warrak El-Hader, Giza, Egypt
WAFFA AHMED SABRY ; Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Warrak El-Hader, Giza, Egypt
EL-SAYED SALEH ABDEL-HAMEED ; Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Warrak El-Hader, Giza, Egypt
EZZAT EL-SAYED ABDEL-LATEEF ; Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Warrak El-Hader, Giza, Egypt

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Abstract

In the present study, antioxidant activity of methanolic extracts of the leaves of seven Egyptian Cassia species was investigated using two methods, the phosphomolybdate method and 1,1 diphenyl-2-picrylhydrazyl radical (DPPH•) scavenging activity method. The results revealed that C. glauca is the most potent species and that the activity of other plant species decreases in the following order C. grandis > C. nodosa > C. fistula > C. didymobtrya > C. occidentalis > C. sophera.
Defatted methanolic extract of the most active plant C. glauca was subjected to fractionation process using different organic solvents such as CHCl3, EtOAc and BuOH. Antioxidant activities of these fractions were investigated and the results showed that ethyl acetate fraction possessed high activity. Total phenolic and flavonoid concentration of each plant extract were determined using the Folin-Ciocaltu reagent and aluminum chloride. Correlation between radical scavenging capacities of extracts and total phenolic concentration was observed.

Keywords

Cassia species; antioxidant; phenolic; flavonoids; DPPH

Hrčak ID:

53500

URI

https://hrcak.srce.hr/53500

Publication date:

1.9.2010.

Article data in other languages: croatian

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