Conference paper

THE STRESS-VULNERABILITY MODEL HOW DOES STRESS IMPACT ON METAL ILLNESS AT THE LEVEL OF THE BRAIN AND WHAT ARE THE CONSEQUENCES?

Cindy Goh ; Clinical School University of Cambridge, UK
Mark Agius ; South Essex Partnership University Foundation Trust, UK, Department of Psychiatry University of Cambridge, UK

Abstract

Introduction: The stress -vulnerability model (Zubin et al. 1977) is and extremely useful model for identifying and treating relapses of mental illness. We accept that human persons carry genetic and other predisposition to mental illness. However, the question arises ast to how stress impacts pn a person in order to cause mentsl illness to develop. Furthermore there arises the issue as to what other effects such stress has on the human body beyond the human brain.
Our aim was to research and integrate the current literature in order to establish how stress impacts on the brain at the cellular level, and to establish wheather there are other consequences for the human body brought about by the impact of stress on the human brain.
Method: Literature Search, using pubmed.
Results: We have identified much literature on how stress affects biological mechanisms within the brain, and how it relates to biological vulnerabilities carried by different individuals.
Conclusion: We have identified communalities in how the interplay between stress and vulnerability occurs in different disease processes.

Keywords

stress; wulnerability; hypothalamo-pituitary axis; epigenetics; depresion-bipolar disorder-schizophrenia

Hrčak ID:

55674

URI

https://hrcak.srce.hr/55674

Publication date:

30.6.2010.

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