Original scientific paper
Diagnostic Value of a Peroral Sucrose Permeability Test in Children with Recurrent Upper Abdominal Pain
Ljerka Pinotić
Mirjana Zečić-Fijačko
Aleksandar Včev
Dubravko Paulini
Silvije Mihaljević
Darko Horvat
Zlatko Mandić
Ana Votava-Raić
Milivoj Boranić
Abstract
The access of ingested sucrose into blood and urine indicates the presence of mucosal lesions in the upper gastrointestinal tract. The study involved 42 children, aged 5–15, having recurrent upper abdominal pain and 43 peers with minor extra-abdominal complaints. Sucrose in urine was determined by thin layer chromatography. The test was
positive in 27 out of 42 children having recurrent abdominal pain (64.3%) and in none
of the control children (x2 = 37.6, p<0.0001). When correlated with endoscopic findings
it was falsely negative in 12 out of 38 patients with endoscopically verified lesions of the stomach or duodenum and falsely positive in 1 out of 4 without lesions. Sensitivity of the test was 68.4%, specificity 97.9%, positive predictive value 96.3%. The test cannot be used as an alternative to endoscopy, but may serve for screening of candidates for it.
Keywords
recurrent abdominal pain; child; sucrose permeability; endoscopy
Hrčak ID:
5608
URI
Publication date:
15.12.2004.
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