Modern Approach to Topical Treatment of Aging Skin
APA 6th Edition
Puizina-Ivić, N., Mirić, L., Čarija, A., Karlica, D. & Marasović, D. (2010). Modern Approach to Topical Treatment of Aging Skin. Collegium antropologicum, 34 (3), 1145-1153. Retrieved from https://hrcak.srce.hr/59399
MLA 8th Edition
Puizina-Ivić, Neira, et al. "Modern Approach to Topical Treatment of Aging Skin." Collegium antropologicum, vol. 34, no. 3, 2010, pp. 1145-1153. https://hrcak.srce.hr/59399. Accessed 11 Dec. 2023.
Chicago 17th Edition
Puizina-Ivić, Neira, Lina Mirić, Antoanela Čarija, Dobrila Karlica and Dujomir Marasović. "Modern Approach to Topical Treatment of Aging Skin." Collegium antropologicum 34, no. 3 (2010): 1145-1153. https://hrcak.srce.hr/59399
Puizina-Ivić, N., et al. (2010). 'Modern Approach to Topical Treatment of Aging Skin', Collegium antropologicum, 34(3), pp. 1145-1153. Available at: https://hrcak.srce.hr/59399 (Accessed 11 December 2023)
Puizina-Ivić N, Mirić L, Čarija A, Karlica D, Marasović D. Modern Approach to Topical Treatment of Aging Skin. Collegium antropologicum [Internet]. 2010 [cited 2023 December 11];34(3):1145-1153. Available from: https://hrcak.srce.hr/59399
N. Puizina-Ivić, L. Mirić, A. Čarija, D. Karlica and D. Marasović, "Modern Approach to Topical Treatment of Aging Skin", Collegium antropologicum, vol.34, no. 3, pp. 1145-1153, 2010. [Online]. Available: https://hrcak.srce.hr/59399. [Accessed: 11 December 2023]
The main processes involved in skin aging are intrinsic and extrinsic. Apart from them, so called stochastic aging connotes cell damage caused by metabolic processes, free radicals and cosmic irradiation. The clinical expression of intrinsic aging include smooth, dry, and thinned skin with accentuated expression lines. It is inevitable and time dependent. Extrinsically aged skin shows signs of photodamage which include appearance of wrinkles, pigmented lesions, actinic keratoses and patchy hypopigmentations. Therapeutic modalities imply photoprotection with sunscreens that prevent sunburns and block ultraviolet irradiation. Other modalities include use of retinoids which regulate gene transcription with subsequent cellular differentiation and proliferation. The topical and peroral administration of »network antioxidants» such as vitamin E and C, coenzyme Q10, alpha-lipoic acid and glutathione, enhance antiaging effect. The other antioxidants such as green tea, dehydroepiandrosterone, melatonin, selenium and resveratrol, have also antiaging and anti-inflammatory effects. Topical bleaching agents such as hydroquinone, kojic acid and azelaic acid can reduce signs of aging. Studies confirm the efficacy of these topical agents in combination with superficial and/or medium depth or deep peeling agents for photodamaged skin treatment. Indications for type of chemical peels according to various clinical diagnosis are done, as well as advantages and disadvantages of differetn types of chemical peels.
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