Original scientific paper

Effects of dexamethasone on the infectivity of Trypanosoma vivax Y486 and the haematological changes in Nigerian domestic chickens (Gallus gallus domesticus).

Adeolu Alex Adedapo ; Department of Veterinary Physiology and Pharmacology, University of Ibadan, Ibadan, Nigeria
Adebowale Bernard Saba ; Department of Veterinary Physiology and Pharmacology, University of Ibadan, Ibadan, Nigeria
Olayinka Adekunle Dina ; Department of Veterinary Physiology and Pharmacology, University of Ibadan, Ibadan, Nigeria
Gbadegesin Moses Akindele Oladejo

Abstract

The study was carried out to investigate how the infectivity of Trypanosoma vivax Y486 could be affected by steroid administration to Nigerian domestic chickens and to observe the haematological and serum biochemistry changes in these chickens infected with Trypanosoma vivax Y486. Results showed that T. vivax Y486 does affect the haematological parameters of Nigerian domestic chickens (Gallus gallus domesticus) as there may be development of anaemia as in large animals. However, there was no patent parasitaemia. In addition, steroid administration when applied at high doses did affect the haematological parameters of the local chickens. It thus showed that serial passaging of T. vivax Y486 can result in infectivity of the Nigerian domestic chickens with trypanosomosis.

Keywords

trypanosomosis; Trypanosoma vivax Y486; dexamethasone; haematology; Gallus gallus domesticus

Hrčak ID:

68647

URI

https://hrcak.srce.hr/68647

Publication date:

20.10.2004.

Article data in other languages: croatian

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