Original scientific paper
Influence of Seasonal Variations on In-Vitro Fertilization Success
Jozo Tomić
Vlatka Tomić
Abstract
This study was designed to investigate the influence of seasonal variations on the number of retrieved ova, fertilization
rate, embryo quality rates and pregnancy rate in IVF cycles. Prospective cohort study was conducted on a total number
of 2140 cycles in infertile patients undergoing their first IVF cycle between 2000 and 2007 in IVF policlinic. c2-test,
Pearson’s correlation coefficient and one-way analysis of variance were used for statistical analyses. Overall fertilization
rate was 77.96% and pregnancy rate 29.15±2.72% per cycle. Seasonal prevalence of pregnancy rate was highest during
fall 33.8±4.5% and lowest during summer 23.4±6.2%, but these differences did not reach statistical significance. The
study did not show any statistically significant differences in the number of retrieved oocyte, fertilization, and embryo
quality according to season. Therefore seasonal changes should not be taken into account in everyday IVF practice.
Keywords
assisted reproduction; embryo quality rate; fertilization rate; pregnancy rate; season
Hrčak ID:
69147
URI
Publication date:
24.6.2011.
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