Original scientific paper

https://doi.org/10.5562/cca1737

Electrochemical Oxidation of 2’-deoxyguanosine-5’-triphosphate on Ionic Liquid Modified Carbon Paste Microelectrode and its Sensitive Detection

Hongwei Gao ; Shandong Entry-Exit Inspection and Quarantine Bureau of People's Republic of China, Qingdao 266002, P. R. China
Yuanyuan Duan ; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China
Li Xu ; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China
Wei Sun ; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China

Abstract

Electrochemical oxidation of 2’-deoxyguanosine-5’-triphosphate (dGTP) was investigated on the ionic liquid modified carbon paste microelectrode by cyclic voltammetry in this paper. The carbon io-nic liquid microelectrode (mCILE) was prepared with ionic liquid 1-ethyl-3-methylimidazolium ethylsul-fate ([Emim][EtOSO3]) as the modifier. Then the electrochemical process of dGTP on the mCILE was recorded with the electrochemical parameters calculated and the oxidation mechanism discussed. Under the optimal conditions differential pulse voltammetric peak current was proportional to the dGTP concen-tration in the range from 1.0×10–6 M to 7.0×10–4 M with the linear regression equation as log(Ipa/A) = 0.77 log(c/mol dm–3) – 4.082 (γ = 0.999). The proposed method showed good selectivity and stability without the interferences of coexisting substances. (doi: 10.5562/cca1737)

Keywords

2’-deoxyguanosine-5’-triphosphate; carbon ionic liquid microelectrode; cyclic voltammetry; electrochemistry; electrooxidation

Hrčak ID:

69692

URI

https://hrcak.srce.hr/69692

Publication date:

30.5.2011.

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