Biochemia Medica, Vol. 22 No. 2, 2012.
Review article
Analysis of censored data
Marko Lucijanic
orcid.org/0000-0002-1372-2040
; Division of Hematology, Department of Internal Medicine, Dubrava University Hospital, Zagreb, Croatia
Mladen Petrovecki
; Department of Clinical Laboratory Diagnosis, Dubrava University Hospital, Zagreb, Croatia; Department of Medical Informatics, Rijeka University School of Medicine, Rijeka, Croatia
Abstract
Analyzing events over time is often complicated by incomplete, or censored, observations. Special non-parametric statistical methods were developed to overcome difficulties in summarizing and com-paring censored data. Life-table (actuarial) method and Kaplan-Meier method are described with an explanation of survival curves. For the didactic purpose authors prepared a workbook based on most widely used Kaplan-Meier method. It should help the reader understand how Kaplan-Meier method is conceptualized and how it can be used to obtain statistics and survival curves needed to completely describe a sample of patients. Log-rank test and hazard ratio are also discussed.
Keywords
actuarial method; censored data; Kaplan-Meier method; Log-rank test; survival analysis
Hrčak ID:
83219
URI
Publication date:
15.6.2012.
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