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Biochemia Medica, Vol. 22 No. 2, 2012.

Review article

Analysis of censored data

Marko Lucijanic orcid id orcid.org/0000-0002-1372-2040 ; Division of Hematology, Department of Internal Medicine, Dubrava University Hospital, Zagreb, Croatia
Mladen Petrovecki ; Department of Clinical Laboratory Diagnosis, Dubrava University Hospital, Zagreb, Croatia; Department of Medical Informatics, Rijeka University School of Medicine, Rijeka, Croatia

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Abstract

Analyzing events over time is often complicated by incomplete, or censored, observations. Special non-parametric statistical methods were developed to overcome difficulties in summarizing and com-paring censored data. Life-table (actuarial) method and Kaplan-Meier method are described with an explanation of survival curves. For the didactic purpose authors prepared a workbook based on most widely used Kaplan-Meier method. It should help the reader understand how Kaplan-Meier method is conceptualized and how it can be used to obtain statistics and survival curves needed to completely describe a sample of patients. Log-rank test and hazard ratio are also discussed.

Keywords

actuarial method; censored data; Kaplan-Meier method; Log-rank test; survival analysis

Hrčak ID:

83219

URI

https://hrcak.srce.hr/83219

Publication date:

15.6.2012.

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