Original scientific paper
Increasing prevalence of breast cancer among Saudi patients attending a tertiary referral hospital: a retrospective epidemiologic study
Ammar Al-Rikabi
; Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Sufia Husain
; Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
Abstract
Aim To determine the pattern of breast diseases among
Saudi patients who underwent breast biopsy, with special
emphasis on breast carcinoma.
Methods A retrospective review was made of all breast biopsy
reports of a mass or lump from male and female patients
seen between January 2001 and December 2010 at
the King Khalid University Hospital, Riyadh, Saudi Arabia.
Results Of 1035 breast tissues reviewed, 939 specimens
(90.7%) were from female patients. There were 690 benign
(65.8%) and 345 (34.2%) malignant cases. In women, 603
(64.2%) specimens were benign and 336 (35.8%) were malignant.
In men, 87 specimens (90.6%) were benign and 9
(9.4%) were malignant. All malignant cases from male patients
belonged to invasive ductal carcinoma and the majority
of malignant cases from female patients belonged
to invasive/infiltrating ductal carcinoma. The proportion
of malignancy was 18% in patients younger than 40 years
and 63.2% in patients older than 60 years. The mean age
of onset for malignancy was 48.6 years. The annual percentage
incidence of malignant breast cancer steadily increased
by 4.8%, from an annual rate of 23.5% in 2000 to
47.2% in 2007.
Conclusion Among Saudi patients, there is a significant
increase in the incidence of breast cancer, which occurs at
an earlier age than in western countries. Continued vigilance,
mammographic screening, and patient education
are needed to establish early diagnosis and perform optimal
treatment.
Keywords
Hrčak ID:
84159
URI
Publication date:
15.6.2012.
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