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Reversal of Thrombocytopenia and Bleeding Tendency in a Preterm Neonate with Recombinant Activated Factor VII: Case Report

Jasminka Jakobović
Diana Butković
Ljiljana Popović
Dubravka Bartolek
Milan Stanojević
Zoran Barčot

Full text: english pdf 151 Kb

page 309-313

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A male neonate, born at 26 weeks of postmenstrual age, with intracranial hemorrhage grade IV and thoracic drainage for artificial tension pneumothorax on day 6 of his life is presented. Despite prior transfusions, the preprocedural hemogram showed marked anemia and thrombocytopenia. To reverse thrombocytopenia and to avoid volume overload, the patient was administered 110 μg kg-1 of recombinant activated factor VII (rFVII a) and drainage of the pneumothorax was performed uneventfully.


Thrombocytopenia – diagnosis, Thrombocytopenia – etiology, Factor VII – therapeutic use, Recombinant proteins – therapeutic use, Infant, premature, Case report

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Article data in other languages: croatian

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