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Collegium antropologicum, Vol. 36 supplement 2 No. 2, 2012.

Review article

Larynx Preservation: Advantages and Limitations

Zoran Rakušić ; University of Zagreb, Zagreb University Hospital Center, Department of Oncology, Zagreb, Croatia
Vesna Bišof ; University of Zagreb, Zagreb University Hospital Center, Department of Oncology, Zagreb, Croatia

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Abstract

For a long time standard treatment approach for resectable squamous cell carcinoma of larynx was surgery with or without subsequent radiotherapy. Surgery, particulary total laryngectomy, has been associated with serious impairment of quallity of life. Between nonsurgical approaches, concurrent cisplatin based chemoradiotherapy has become a very promising treatment modality for larynx preservation. However, concurrent chemotherapy has been associated with serious toxicity. The most recent treatment approach in larynx preservation is related to taxan based induction chemotherapy.

Keywords

larynx preservation; induction chemotherapy; concurrent chemoradiotherapy

Hrčak ID:

96613

URI

https://hrcak.srce.hr/96613

Publication date:

2.1.2013.

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