Short communication, Note

Determination of Benzene in Urine by Static Headspace Gas Chromatography

Ljiljana Skender
Irena Brčić
Silva Žužul

Abstract

This paper describes the application of static headspace gas chromatography in determining benzene in urine. The method was analytically validated for sensitivity (DL=42 ng/l), repeatability (RSD=3% and 4%), and accuracy (71%), and was applied in measuring urine benzene in nonsmokers (N=14) and smokers (N=18). All urine samples had measurable benzene concentrations. The method proved sensitive enough to establish a significant statistical difference (P<0.000614) in urine benzene concentrations between smokers (mean=760; range =181–1869 ng/l) and nonsmokers (mean=214; range=61–515 ng/l).

Keywords

analytical validation; nonsmokers; smokers

Hrčak ID:

446

URI

https://hrcak.srce.hr/446

Publication date:

23.12.2002.

Article data in other languages: croatian

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