Original scientific paper

Antithrombin III in healthy dogs and in dogs suffering from babesiosis.

Vladimir Mrljak orcid.org/0000-0002-0723-7815 ; Clinic for Internal Diseases with Chair of Cynology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Renata Barić Rafaj ; Clinic for Internal Diseases with Chair of Cynology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Velimir Sušić ; Department of Animal Husbandry, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Vesna Matijatko ; Clinic for Internal Diseases with Chair of Cynology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Nada Kučer orcid.org/0000-0001-9378-7110 ; Clinic for Internal Diseases with Chair of Cynology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Ivana Kiš ; Clinic for Internal Diseases with Chair of Cynology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia

Abstract

Antithrombin III (AT III) was measured in 15 dogs with Babesia canis infection and in 15 healthy dogs. Blood samples for control group and patients were taken before the therapy with imidocarb dipropionat and on the 1st and 5th days after the therapy. Measurements of AT III activity in canine plasma with thrombin dependent chromogenic substrate assay using automatic analyzer showed a good within-run precision. The results were expressed as proportions of the norm. Value for AT III before the therapy was lower than in the control group. Activity of AT III was higher on the post-treatment day 5 than before the therapy. A survey of individual data demonstrated that in 2 dogs the pre-treatment AT III values were 0.66 and 0.79, respectively, showing consumption inhibitors of coagulation.

Keywords

babesiosis; dog; antithrombin III

Hrčak ID:

67395

URI

https://hrcak.srce.hr/67395

Publication date:

20.12.2005.

Article data in other languages: croatian

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